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Updated: Jan 13, 2026

Yeast As a Chassis for Developing Functional Assays to Study Human P53
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Yeast As a Chassis for Developing Functional Assays to Study Human P53

Published on: August 4, 2019

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可转移元素的局部特异性转录调节由p53进行

Julia M Freewoman1, Andrew J Rosato1, Thomas M Russell1

  • 1Thomas H. Gosnell School of Life Sciences, Rochester Institute of Technology, Rochester, NY, USA.

Cell cycle (Georgetown, Tex.)
|January 8, 2026
PubMed
概括

瘤抑制剂p53调节可移植元素 (TE). 新的计算方法揭示了TEs在正常细胞中激活,但在癌细胞中抑制p53结合,突出显示染色质的上下文作用.

关键词:
在P53中,P53是P53染色体的背景 染色体的背景特定位置的特定位置.转录规则 转录规则 转录规则可转移的元素可以转移.

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