原发性偏甲状腺功能障碍症的神经精神表现
Marco Mairinger1,2, Godber Mathis Godbersen1,2, Siegfried Kasper3,4
1Department of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
原发性偏甲状腺症 (PHPT) 可以导致神经精神症状,如抑郁和焦虑. 副甲状腺切除手术通常可以改善这些症状,但在症状管理方面的使用指南有所不同.
科学领域:
- 内分泌学 在内分泌学.
- 神经精神病学是一种神经精神病学.
- 手术科学 手术科学
背景情况:
- 神经精神表现影响了大约25%的原发性甲状腺功能障碍症 (PHPT) 患者.
- 症状范围从常见的抑郁,焦虑,疲劳和认知功能障碍到更罕见的状态,如躁狂,妄想和精神病.
- 病理生理学是多因素的,涉及升高的帕拉荷尔蒙,高血症,以及对神经传递和神经炎症的影响.
研究的目的:
- 审查PHPT中神经精神疾病表现的病理生理学理解.
- 要总结与PHPT相关的常见神经精神症状.
- 为临床医生提供基于证据的工具,以有效检测这些症状.
主要方法:
- 文献综述侧重于病理生理机制,症状表现和诊断工具.
- 突出用于PHPT研究精神病症状负担的心理测量问卷.
- 讨论查截止值和在临床实践中的实际实施.
主要成果:
- 副甲状腺切除术越来越多地因其在缓解PHPT患者神经精神病症状方面的有效性而得到认可.
- 有证据表明,手术后抑郁症,焦虑,疲劳和认知功能障碍的持续改善.
- 临床实践指南在神经精神病症状是否单独证明甲状腺外科手术方面存在差异.
结论:
- 建议基于症状的治疗方法用于PHPT患者的神经精神疾病的表现.
- 建议与其他治疗一起评估手术干预 (副甲状腺切除术).
- 关于PHPT中神经精神病症状的手术指示,需要进一步的研究和指导方针共识.
更多相关视频
07:12Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging
Published on: August 17, 2022
07:13Two Techniques to Create Hypoparathyroid Mice: Parathyroidectomy Using GFP Glands and Diphtheria-Toxin-Mediated Parathyroid Ablation
Published on: March 14, 2017
相关概念视频
Chronic Kidney Disease II: Clinical Manifestations
Parkinson's Disease: Overview
The Parathyroid Glands
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by...
Positive Symptoms of Schizophrenia: Hallucinations and Delusions
Thought Disorders
Disorganized and unusual thought processes mark thought disorders in schizophrenia. One key feature is disorganized speech, where an individual's conversation includes...
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
Disorders of the Nervous Tissue
Homeostatic Imbalances:
Alzheimer's disease manifests as a gradual decline in memory and cognitive abilities, attributed to the buildup of amyloid plaques and neurofibrillary tangles in the brain.
Parkinson's disease arises from the...
