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Updated: Jan 13, 2026

Telomere Length and Telomerase Activity; A Yin and Yang of Cell Senescence
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Telomere Length and Telomerase Activity; A Yin and Yang of Cell Senescence

Published on: May 22, 2013

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一种对端粒特异性端粒长度调节的机制

Gabriela M Teplitz1, Emeline Pasquier1, Erin Bonnell1

  • 1Department of Microbiology and Infectiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke J1E 4K8, Canada.

Nucleic acids research
|January 8, 2026
PubMed
概括

端粒长度调节不是统一的;这项研究揭示了端粒特异性设置长度控制的机制. 特定的DNA区域和蛋白质如Sir4和Tbf1调节端粒长度,影响染色体稳定性和细胞衰老.

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