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Updated: Jan 13, 2026

Efficient Sampling of Genetically Encoded Biosensor Design Space Enabled with a Design of Experiments and Automation Workflow
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Efficient Sampling of Genetically Encoded Biosensor Design Space Enabled with a Design of Experiments and Automation Workflow

Published on: October 17, 2025

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一个统一的计算框架,用于定量设计和优化跨细菌物种的转录调节

Tianze Wang1,2, Ronghui Xie1, Zhuo Ma1,3

  • 1State Key Laboratory of Quantitative Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, 1068 Xueyuan Avenue, Shenzhen 518055, China.

Nucleic acids research
|January 8, 2026
PubMed
概括

我们开发了一个模块化热力学模型,T-Pro,用于精确的转录调节建模. 这一框架显著改善了在多种细菌物种中合成生物学中的遗传电路设计.

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