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一个基于应用的新型测试,用于快速选嗅觉功能障碍
Benjamin J Bernard1, Omer Baker2, Alena Pauley2
1Department of Otolaryngology-Head and Neck Surgery, University of California, San Diego, La Jolla.
JAMA otolaryngology-- head & neck surgery
|January 8, 2026
概括
一个新的移动应用程序有效地选嗅觉功能障碍 (OD),这是一个常见的情况. 这种工具快速,可靠,与现有的临床用气味测试相关.
科学领域:
- 神经学 神经学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 医学诊断 医学诊断 医学诊断
背景情况:
- 嗅觉功能障碍 (OD) 是普遍存在的,并且经常被低诊断,造成发病率和死亡率的风险.
- 目前的气味测试通常是昂贵的,耗时的,并且难以扩展.
研究的目的:
- 评估一种基于移动应用程序的新型,自我管理的嗅觉查工具的诊断性能.
主要方法:
- 一项诊断研究涉及484名英语成年人 (≥18岁) 在美国学术医疗中心.
- 参与者完成了5项移动应用气味识别测试;一个子组也进行了比较测试.
主要成果:
- 这种新型测试显示出良好的诊断准确性,曲线下的面积为0.87 (95% CI,0.78-0.96).
- 敏感度为74% (95% CI,51%-88%) 和特异性为86% (95% CI,72%-93%) 在切断值<3.3时.
- 测试得分与对比测试 (r=0.74) 和主观嗅觉 (r=0.34) 相对相关,显示可接受的内部一致性.
结论:
- 基于移动应用程序的嗅觉查工具是一种快速,可靠的方法来检测OD.
- 该工具显示出广泛临床使用和纵向监测嗅觉功能的潜力.
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