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抗菌和调节温度的纤维素纤维用于增强伤口愈合和感染控制

Xiongwei Dong^1,2, Peng Li^1,3, Yihang Tang⁴

¹National Local Joint Engineering Laboratory for Advanced Textile Processing and Clean Production, School of Bioengineering and Health, Wuhan Textile University, Wuhan 430073, China.

Biomacromolecules

|January 8, 2026

概括

新的Lyocell纤维含有阿洛因和石墨烯氧化物 (GO) 为伤口护理提供抗菌和热调节. 这些功能性纤维促进愈合,并防止感染,对医疗织品和个人安全有希望.

科学领域:

材料科学材料科学材料科学
生物医学工程生物医学工程
织科学织科学

背景情况:

具有抗微生物和热调节特性的多功能织品对于伤口护理和个人保护至关重要.
现有的材料往往缺乏先进应用所需的综合功效.

研究的目的:

开发具有集成抗菌和热调节功能的新型Lyocell纤维.
为了评估这些功能纤维在体外和体内用于伤口愈合应用的性能.

主要方法:

在Lyocell纤维上对aloin进行共价接种.
将石墨烯氧化物 (GO) 和相变微囊 (PCM) 集成到纤维结构中.
纤维形态的表征,热特性,机械强度和抗菌功效.
在体内研究,使用金黄色葡萄球菌感染的老鼠伤口模型.

主要成果:

最佳的功能纤维 (功能纤维2) 显示出显著的相变度 (27.61 J/g) 和良好的机械性能.
在体外完全抑制金黄色葡萄球菌和大肠杆菌的生长,在30个洗周期后具有持续的抗菌疗效.
在老鼠中加速伤口愈合,将伤口直径减少约77%,预防感染,增强血管生成.

结论:

开发的与阿洛因和GO集成的Lyocell纤维具有出色的抗菌和温度调节特性.
这些功能纤维显示出在先进的防护织品,医疗用品和伤口护理应用中使用的巨大潜力.
该研究强调了一种创造多功能智能织品的有希望的方法.

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