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Updated: Jan 13, 2026

Optimized LC-MS/MS Method for the High-throughput Analysis of Clinical Samples of Ivacaftor, Its Major Metabolites, and Lumacaftor in Biological Fluids of Cystic Fibrosis Patients
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Optimized LC-MS/MS Method for the High-throughput Analysis of Clinical Samples of Ivacaftor, Its Major Metabolites, and Lumacaftor in Biological Fluids of Cystic Fibrosis Patients

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埃维纳库马布在5至17岁的患者中使用,患者患有同卵性家族性高胆固醇血清症

Robert S Rosenson1, Eliot A Brinton2, Daniel Gaudet3

  • 1Metabolism and Lipids Program, Mount Sinai Fuster Heart Hospital, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Atherosclerosis
|January 8, 2026
PubMed
概括

埃维纳巴可显著降低LDL-C在患有同卵性家族高胆固醇血症 (HoFH) 的儿童和青少年. 这种新疗法被证明比标准治疗更有效,为管理这种罕见的遗传疾病提供了新的选择.

关键词:
青少年健康/药物 青少年健康/药物心脏病学 心脏病学心血管疾病 心血管疾病

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