功能性胆囊疾病:我们是否缺少胆结石?
Tan Jun Guang Kendric1, Sharie Ann Apikotoa1, Zi Qin Ng1
1General Surgery Registrar, St John of God Midland Hospital, Midland, Western Australia, Australia.
World journal of surgery
|January 8, 2026
概括
功能性胆囊疾病 (FGBD) 诊断可能会错过胆结石. 组织病理学发现18.5%的FGBD患者有胆结石,突出显示胆道疼痛的成像限制.
科学领域:
- 胃肠病学 胃肠病学
- 肝病学 肝病学是一种肝病学.
- 诊断成像 诊断成像 诊断成像
背景情况:
- 功能性胆囊乱 (FGBD) 通过ROME IV标准诊断,涉及没有胆结石但胆囊射出分数低的胆道疼痛.
- 组织病理学分析有时会在被诊断患有FGBD的患者中发现胆结石 (胆结石).
- 这项研究量化了FGBD错过的胆结石,旨在减少误诊.
研究的目的:
- 为量化诊断有功能性胆囊疾病的患者发生的组织病理性胆囊病的发病率.
- 评估错过胆结石对FGBD诊断和患者结局的影响.
- 突出了手术前成像在识别胆结石在胆道疼痛患者的局限性.
主要方法:
- 在2015年11月至2024年4月期间,对484名接受肝胆氨酸扫描 (HIDA) 的患者进行了回顾性队列研究.
- 在手术前诊断出FGBD的患者的分析.
- 对胆囊切除术后的组织病理学发现和患者症状解决的审查.
主要成果:
- 5.6%的患者在手术前被诊断出FGBD.
- 在这些患者中,18.5%的患者患有组织病理性胆病,尽管手术前的成像显示了相反的情况.
- 70%的真正胆囊功能障碍患者在胆囊切除术后经历了症状缓解.
结论:
- 功能性胆囊疾病是不分化的腹痛的一个显著原因.
- 通过手术前成像,小结石 (小结石) 可能会在五分之一的患者中被忽略.
- 考虑胆道疼痛的功能方面以及对成像局限性的认识对于减少虚假阴性病发率至关重要.
相关概念视频
Diseases of the Liver and Gallbladder
1.8K
Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
1.8K
Gallbladder
2.0K
The gallbladder is a small, pear-shaped organ that plays a crucial role in our digestive system. Measuring about 10 cm in length, it is comparable in size to a kiwi fruit and is located in a hollow area on the lower surface of the liver. The gallbladder's primary function is to store and concentrate bile, a fluid produced by the liver that aids in digestion.
The gallbladder's anatomy consists of three regions: the fundus, body, and neck. Extending from the neck, the cystic duct joins...
The gallbladder's anatomy consists of three regions: the fundus, body, and neck. Extending from the neck, the cystic duct joins...
2.0K
Chronic Bowel Disorders: Introduction
743
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
743
Other Disorders of Digestive System
1.4K
The gastrointestinal tract is susceptible to various disorders. If the lower esophageal sphincter is damaged, stomach acid can flow back into the esophagus, causing irritation and inflammation of the lining. This condition is called gastroesophageal reflux disease (known as heartburn) and may cause chest pain and difficulty swallowing. In the stomach, prolonged use of nonsteroidal anti-inflammatory drugs like aspirin, chronic alcohol consumption, bacterial infections such as Helicobacter...
1.4K
Gastrointestinal Motility Disorders
1.1K
Gastrointestinal or GI motility disorders are characterized by irregular gastrointestinal tract movements, disrupting food transit from the mouth to the anus. They are caused by damage or dysfunction in gut muscles or nerves. These disorders can cause symptoms such as severe constipation, diarrhea, abdominal pain, and swallowing difficulties. Disorders can affect any segment of the GI tract and range widely in severity, from common conditions like GERD to life-threatening conditions like...
1.1K
Acute Pancreatitis II: Clinical Manifestations and Management
736
Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
736


