基于酸盐的法医血液替代品,模仿整个血液凝固和干燥特性在滴水污点和池中
Erin Giroux1, Shaijieni Kannan1, Theresa Stotesbury2
1Applied Bioscience Graduate Program, Ontario Tech University, 2000 Simcoe St N, Oshawa, ON, Canada.
Science & justice : journal of the Forensic Science Society
|January 8, 2026
概括
法医血液替代品 (FBS) 被测试了干燥动态. 配方FBS2更好地模仿全血凝固,使FBS1和FBS2都适合用于血液染色模式分析培训和研究.
科学领域:
- 法医科学 法医科学 法医科学
- 材料科学 材料科学 材料科学
- 流体动力学 流体动力学
背景情况:
- 法医血液替代品 (FBS) 为训练和研究提供了比真血更好的优势.
- 之前没有研究过FBS的干燥动态.
- 了解干燥行为对于准确的血迹模式分析至关重要.
研究的目的:
- 为了比较两种基于酸盐的水凝FBS配方 (FBS1和FBS2) 的干燥动态与全牛血液.
- 评估这些FBS配方适合于血液染色模式分析培训和研究.
- 研究如何修改聚合物和交叉连接剂度影响FBS干燥行为.
主要方法:
- 制备了两种基于酸盐的水凝FBS配方 (FBS1和FBS2),粘度不同.
- 滴滴斑点和池 (2,10,500微升) 的FBS和牛血沉积在玻璃瓦和棉衣上.
- 观察了干燥动态,并通过风力测量表征了流体特性 (振荡幅度,流量和时间扫描).
主要成果:
- 在无孔上,FBS在很大程度上复制了血液的早期干燥阶段,但缺乏最后阶段的裂和解结.
- 与FBS1.1相比,FBS2的干燥特性更接近全血,特别是在池中.
- 在多孔棉球衣上,FBS的两种配方都类似于血液,干燥更轻,但有一个深色的边缘.
结论:
- 修改聚合物和离子交叉连接剂度可以操纵FBS的物理性质,在染色过程中模仿血液.
- FBS1适合滴滴斑点,而FBS2更好地模仿整体血液在更大的斑点凝固期间的粘性行为.
- 这两种FBS配方都适合在法医培训和研究中生成血迹,FBS2显示了对聚合污点的改进模仿.
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