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Updated: Jan 13, 2026

Cell Population Analyses During Skin Carcinogenesis
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Published on: August 21, 2013

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在特定的皮肤祖先群体中,SOX2赋予了瘤的容许性

Patricia P Centeno1,2, Christopher Chester3,4, Georgios Kanellos5

  • 1Cancer Research UK Scotland Institute, Glasgow, UK. P.Centeno@crukscotlandinstitute.ac.uk.

Nature communications
|January 8, 2026
PubMed
概括

皮肤干细胞和原始细胞对导致皮肤状细胞癌 (cSCC) 的突变有不同的反应. 原始体中的SOX2过度表达,与MAPK激活,使得瘤迅速形成.

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