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Updated: Jan 13, 2026

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ERK/Smurf1通过促使Caspase-11无处不在的化来调节非正规的烧

Chenglong Zhu1,2,3, Wangzheqi Zhang2,3, Yan Liao2,3

  • 1National Key Laboratory of Immunity and Inflammation, Naval Medical University, Shanghai, China.

Cell death and differentiation
|January 8, 2026
PubMed
概括

E3 泛基素结合酶 Smurf1 负面调节了败血症中非正规的炎症酶途径. Smurf1 缺乏会加剧败血症死亡率,而 Smurf1 补充剂会减轻死亡率,突出其治疗潜力.

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