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Updated: Jan 13, 2026

Caenorhabditis elegans as a Model System for Discovering Bioactive Compounds Against Polyglutamine-Mediated Neurotoxicity
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阿格洛多A-J,来自Aglaia odorata的多维神经保护作用的未描述的类

Meng Ding1, Yue-Han Wang1, Chen-Hao Liu1

  • 1State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, PR China.

Natural products and bioprospecting
|January 8, 2026
PubMed
概括

这项研究从Aglaia odorata Lour.中分离出了新型的三烯酸和二烯酸. 几种化合物显示出显著的神经保护作用,包括对氧气-葡萄糖剥夺/反损伤和兴奋毒性.

关键词:
阿格莱亚的气味是洛尔的.这是一种抗ferroptosis.这是一种抗神经炎症的药物.迪特尔佩诺类动物 (Diterpenoids) 是一种形类动物.神经保护性活动神经保护性活动这种类型的Triterpenoids.

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