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用超声波引导的甲型肉毒素治疗肩部疼痛:随机对照试验的元分析

Shiying Zhuang¹, Xiaoli Zhang¹, Cheng Lin²

¹Department of Rehabilitation Medicine, School of Health, Fujian Medical University, No. 1 Xuefu North Road, University Town, Fuzhou, Fujian, 350122, China.

BMC musculoskeletal disorders

|January 8, 2026

概括

超声波引导的肉毒素A型注射显著减少肩膀疼痛,改善上肢功能. 需要进一步的高质量研究来证实长期疗效.

科学领域:

整形外科整形外科整形外科
疼痛管理疼痛管理
神经学神经学

背景情况:

肩部疼痛是一种普遍的疾病,影响了许多人.
甲型玻尿素毒素在减轻肩部疼痛方面表现有前途.
进行了系统性审查和元分析,以评估超声波引导的甲型肉毒素对肩部疼痛的治疗.

研究的目的:

综合现有关于超声波导向肉毒素A型对肩部疼痛疗效的科学证据.
量化这种治疗对疼痛减轻和功能改善的综合作用.

主要方法:

在多个数据库 (PubMed, Embase, Scopus, CENTRAL, CNKI, Wanfang, VIP) 进行了全面的文献搜索.
关键词包括"超声波"",A型玻尿素毒素"和"肩部疼痛".
分析了10项涉及533名患者的研究数据,使用随机效应模型计算标准化平均差异 (SMD) 和95%置信区间 (CI) 来计算各种结果指标.

主要成果:

超声波引导的甲型肉毒素显著改善了肩部疼痛 (SMD = -1.1,P < 0.001).
在上肢Fugl-Meyer评估 (UEFMA) 评分 (SMD = 1.43,P = 0.003) 和曲 (SMD = 1.28,P < 0.001) 和外部旋转 (SMD = 1.66,P < 0.001) 的运动范围 (ROM) 中观察到积极影响.
在肩膀绑架的ROM (SMD = 0.8,P = 0.01) 和修改的巴特尔指数 (MBI) 评分 (SMD = 1.33,P = 0.02) 中发现了轻微的改善.

结论:

超声波引导的肉毒素A型注射显示了减少肩膀疼痛和增强上肢功能,ROM和生活质量的潜在益处.
由于包括小样本大小,异质性和可能的出版偏差在内的潜在限制,应谨慎解释研究结果.
建议进一步进行高质量的大规模研究,以验证长期疗效,并巩固这种治疗方式的证据.

关键词:

这是一个BoNT-A.注射方式注射方式进行元分析分析.生活质量生活的质量.在这里,我们可以使用ROM ROM ROM.肩膀疼痛肩膀疼痛肩膀疼痛肩膀疼痛超声波引导的超声波指导上肢的功能上肢的功能.

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