在良性前列腺增生手术中感染风险因素的评估:法国多中心TOCUS研究的结果
Mathilde Chapuis1, Stessy Kutchukian2, Pierre Bigot3
1Département d'urologie Centre Hospitalier Universitaire, Guadeloupe, France.
The world journal of men's health
|January 9, 2026
概括
无症状细菌尿 (ABU) 在良性前列腺增生 (BPH) 手术后显著增加感染并发症. 手术技术不会影响感染风险,这凸显了在BPH患者中管理ABU的重要性.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 传染性疾病 传染性疾病
- 外科手术的结果
背景情况:
- 良性前列腺增生症 (BPH) 是老年男性常见的疾病,通常需要手术干预.
- 最近BPH手术技术的进步旨在改善结果并减少并发症.
- 在BPH手术后,术后感染仍然是一个问题,需要对相关风险因素进行调查.
研究的目的:
- 为了确定与手术后感染并发症相关的因素,在接受BPH手术治疗的患者.
- 评估无症状细菌性尿病 (ABU) 和手术前抗生素策略对感染风险的影响.
主要方法:
- 一项多中心的回顾性研究 (TOCUS) 包括从2016年1月到2023年4月接受BPH手术的患者.
- 主要终点是手术后30天内发生的感染性并发症,包括手术部位感染或发烧性尿路感染 (UTI).
- 分析了手术前尿液培养,抗生素治疗和患者病史的数据.
主要成果:
- 在包括的498名患者中,术后感染率为5.1%.
- 尿路感染史和积极的手术前尿液培养 (单微生物,双微生物或多微生物) 与感染风险增加密切相关.
- 手术前的抗生素治疗和抗生素预防没有显示出与减少感染并发症的显著关联.
- 不同的手术技术之间没有观察到感染率的显著差异.
结论:
- 手术技术不是BPH手术后感染风险的重要因素.
- 无症状的细菌尿,无论微生物负载如何,是BPH手术后感染并发症的强有力的危险因素.
- 在这种情况下,目前的手术前抗生素策略似乎无法减轻与ABU相关的风险.
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