与安慰剂相比,富于血小板的血在侧面脊髓炎患者中不会改善疼痛或功能:随机临床试验的元分析
César Romero Antunes Júnior1, Ramon Sampaio Souza Santos2, Eduardo Silva Reis Barreto1
1Federal University of Bahia, Salvador, Brazil.
The American journal of sports medicine
|January 9, 2026
概括
与安慰剂相比,富血小板血 (PRP) 注射并没有显著改善网球手肘 (侧面表皮质炎) 的疼痛或功能. 目前的证据不支持PRP作为这种常见疾病的推治疗方法.
科学领域:
- 整形外科 整形外科 整形外科
- 再生医学是一种再生医学.
- 肌肉骨系统疾病 肌肉骨系统疾病
背景情况:
- 侧侧上腺炎或网球肘是一种常见的疾病,导致疼痛和功能限制.
- 富血小板血 (PRP) 作为一种再生疗法正在研究中,但其有效性仍在争论中.
研究的目的:
- 通过系统性审查和元分析,评估PRP与安慰剂对网球肘的疗效和安全性.
- 评估疼痛缓解和功能改善在治疗后的各种时间点.
主要方法:
- 随机临床试验 (RCT) 的系统审查和元分析,具有1级证据.
- 在PubMed,Scopus,Embase和Cochrane CENTRAL搜索了相关的RCT.
- 分析了主要结果 (疼痛,功能) 和次要结果 (不良事件,握力).
主要成果:
- 分析了6项涉及355名患者的RCT.
- 与安慰剂相比,PRP在4,8-12或24-26周的疼痛缓解或功能改善方面没有显著差异.
- 在PRP和安慰剂组之间没有观察到不良事件的显著差异.
结论:
- 与安慰剂相比,PRP治疗对侧面表皮炎没有显著的缓解疼痛或功能改善.
- 目前可用的RCT的证据不支持对网球手肘的PRP的推.
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