华德纳菲尔对长期糖尿病患者的影响,比较不同剂量的勃起功能障碍,水平和伴侣满意度
Ahmed ElSayed Abdellatif1, Ahmed Mahmoud Abdelbary1, Ahmed M Ragheb1
1Beni-Suef governorate - Egypt, Department of Urology, Faculty of Medicine, Beni-suef University.
Arab journal of urology
|January 9, 2026
概括
华迪纳菲尔有效地治疗II型糖尿病患者的勃起功能障碍 (ED). 每天服用10毫克一次或每天两次服用5毫克的剂量改善了ED,水平和伴侣满意度.
科学领域:
- 内分泌学 在内分泌学.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 药理学 药理学是指药理学的学科.
背景情况:
- 糖尿病患者比非糖尿病男性更早,更频繁地出现勃起功能障碍 (ED).
- 糖尿病男性中ED的患病率在20%至75%之间.
研究的目的:
- 评估在II型糖尿病 (DM) 患者中使用不同剂量的瓦德纳菲尔的疗效和安全性.
- 评估瓦德纳菲尔对水平和伴侣满意度的影响.
主要方法:
- 一项随机临床试验,涉及102名II型DM患者,在2021年10月至2022年10月期间患有ED.
- 患者被随机分为四组,接受瓦德纳菲尔:每天一次服用5mg,两次服用5mg,一次服用10mg或每天两次服用10mg.
- 使用国际勃起功能指数 (IIEF) 测量勃起功能,对勃起功能障碍治疗满意度清单 (EDITS) 的伴侣满意度,并在治疗前和后监测丸激素水平.
主要成果:
- 在每天接受10毫克一次和每天两次接受5毫克的患者之间观察到EDITS和IIEF-15分数的统计学上显著差异 (p=0.001).
- 在所有vardenafil剂量组中,丸激素水平增加,在较高剂量时效果更为明显.
- 患者的平均年龄为55.45±8.142岁,平均HbA1c为8.8%±1.5.
结论:
- 华迪纳菲尔,每天服用10毫克一次或每天两次服用5毫克,是长期患有II型糖尿病患者的ED的有效治疗选择.
- 这些特定的vardenafil疗法在改善勃起功能和伴侣满意度方面表现出有效性.
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