儿科甲状腺风暴中的发作:两个病例和文献综述
Sayaka Kawashima1, Chisumi Sogi1,2, Dai Suzuki1
1Department of Pediatrics, Tohoku University Graduate School of Medicine, Sendai, Japan.
概括
与成年人不同的是,儿童的甲状腺风暴发作可能不表明严重的后果. 这项研究表明,儿童甲状腺风暴病例中的发作往往具有有利的预后,因此需要仔细评估.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 神经学 神经学
- 关键护理医学 关键护理医学
背景情况:
- 甲状腺风暴是一种严重的甲状腺毒症并发症,危及生命.
- 成年人的诊断标准通常集中在中枢神经系统 (CNS) 症状上,包括由于潜在的不可逆转损伤而引起的发作.
- 儿童的发作值较低,这可能导致儿童甲状腺风暴病例的严重程度被高估.
研究的目的:
- 报告儿科甲状腺风暴病例与发作.
- 为了审查儿童甲状腺风暴中发作的文献.
- 为了评估儿科甲状腺风暴中发作的预后意义.
主要方法:
- 关于两名患有甲状腺风暴,发作,发烧和低心率的儿科患者的病例报告.
- 对84名患有甲状腺风暴的儿童和青少年进行系统性文献综述.
- 对儿科甲状腺风暴病例中发病率和结果的分析.
主要成果:
- 介绍了两例患有发作的甲状腺风暴的儿科病例;一个需要重症监护,而另一个在治疗后得到改善.
- 一项文献审查发现了16例 (19%) 儿科甲状腺风暴与发作的病例.
- 与青少年 (7.3%) 相比,婴儿 (30.0%) 和幼儿 (30.4%) 的发作患病率更高.
- 几乎所有报告的发作病例都有有利的结果.
结论:
- 儿科甲状腺风暴中的发作可能与预后不佳无关,这与成人诊断标准相反.
- 虽然发作在儿科甲状腺风暴中更常见,并且通常具有有利的结果,但由于病情的严重程度,它们的存在需要仔细评估.
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