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Updated: Jan 13, 2026

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
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A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer

Published on: March 6, 2018

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一个MYC家族开关:L-MYC驱动和维护前列腺癌中神经内分泌血统程序

Jeyaluxmy Sivalingam, Kyung Hyun Cho, Yingli Shi

    bioRxiv : the preprint server for biology
    |January 9, 2026
    PubMed
    概括

    通过重编程细胞和抑制AR信号,L-MYC (MYCL) 驱动神经内分泌前列腺癌 (NEPC). 这项研究揭示了NEPC中的MYC家族开关,确定L-MYC是这种攻击性癌症亚型的关键调节者.

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    Published on: November 19, 2019

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