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Updated: Jan 13, 2026

A Restriction Enzyme Based Cloning Method to Assess the In vitro Replication Capacity of HIV-1 Subtype C Gag-MJ4 Chimeric Viruses
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艾滋病毒Nef放大了机械异质性,以促进免疫逃避

Louise Leyre1,2, Farah Mustapha3, Alberto Herrera1,2

  • 1Infectious Disease Division, Weill Cornell Medicine, New York, NY, USA.

bioRxiv : the preprint server for biology
|January 9, 2026
PubMed
概括

人类免疫缺陷病毒 (HIV) 感染的T细胞通过变得更柔软而逃避免疫检测,这是一个阻碍细胞毒性T淋巴细胞 (CTL) 死亡的生物物理机制. 操纵细胞硬性提供了一个潜在的艾滋病毒治疗策略.

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