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Updated: Jan 13, 2026

Evaluation of a Reliable Biomarker in a Cecal Ligation and Puncture-Induced Mouse Model of Sepsis
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Evaluation of a Reliable Biomarker in a Cecal Ligation and Puncture-Induced Mouse Model of Sepsis

Published on: December 9, 2022

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质子激活化物通道1 (PACC1) 对于对细菌败血症的天生的宿主防御至关重要

Lucien P Garo, Kevin Brueck, Sarah Walachowski

    bioRxiv : the preprint server for biology
    |January 9, 2026
    PubMed
    概括

    对酸敏感的化物通道PACC1 (PAC/ASOR/TMEM206) 对抗细菌败血症的宿主防御至关重要. 删除PACC1会损害细菌清除,增加败血症致死率,突出其在天生的免疫力中的保护作用.

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