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Updated: Jan 13, 2026

Detecting Somatic Genetic Alterations in Tumor Specimens by Exon Capture and Massively Parallel Sequencing
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Detecting Somatic Genetic Alterations in Tumor Specimens by Exon Capture and Massively Parallel Sequencing

Published on: October 18, 2013

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利用人类的病原体来改善体质变体检测

Qichen Fu, Zilan Xin, Benpeng Miao

    bioRxiv : the preprint server for biology
    |January 9, 2026
    PubMed
    概括

    基于图形的泛基因组通过增强读取对齐和重建个性化的基因组来提高体质变异检测准确度. 这种方法克服了像GRCh38这样的线性引用的局限性,以获得更可靠的变量调用.

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    Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay EMSA and DNA-affinity Precipitation Assay DAPA11:35

    Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay EMSA and DNA-affinity Precipitation Assay DAPA

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