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Updated: Jan 13, 2026

Using RNA-sequencing to Detect Novel Splice Variants Related to Drug Resistance in In Vitro Cancer Models
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Published on: December 9, 2016

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转录组范围的映射揭示了白金癌症药物的RNA依赖机制

Arun Krishnaraj, Xinrui Wei, Richi Thakral

    bioRxiv : the preprint server for biology
    |January 9, 2026
    PubMed
    概括

    作为一种关键的化疗药物,西斯普拉丁与RNA G-四重复合体结合,影响其有效性,并揭示了一种新的基于RNA的作用机制. 这种药物-RNA相互作用预测了患者对基化疗的反应.

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