邻近的背侧前额叶皮层 (DLPFC) 区域参与不同的大规模网络,以不同的方式招募社会和认知控制功能
bioRxiv : the preprint server for biology
|January 9, 2026
概括
人体前额叶皮层 (PFC) 的相邻区域表现出专门的功能. 一个背侧PFC区域处理社会认知 (思想理论),而一个邻近的区域处理工作记忆,揭示PFC内部的功能专业化.
科学领域:
- 神经科学是一个神经科学.
- 认知神经科学 认知神经科学
- 神经成像是一种神经成像.
背景情况:
- 人类前额叶皮层 (PFC) 呈现异质性,子身上有明显的解剖预测,表明潜在的区域专业化.
- 以前的人类研究表明,空间和语言处理的PFC区域与灵活的认知控制区域相邻.
研究的目的:
- 调查参与社会处理 (思想理论,ToM) 和工作记忆的背侧PFC (DLPFC) 区域的功能专业化.
主要方法:
- 在13名参与者中使用了个体内精确的神经成像.
- 基于个体解剖学的平行分布网络中嵌入的确定邻近的DLPFC区域.
- 评估对理论思维和工作记忆任务的功能反应.
主要成果:
- 在相邻的DLPFC区域之间观察到强大的功能双解离.
- 一个DLPFC地区显示对ToM任务的优先招聘.
- 一个相邻的DLPFC区域被工作记忆任务需求优先招募.
结论:
- 调查结果支持PFC内部的功能专业化增加超出了以前的估计.
- 相邻的PFC区域的专业化与它们所居住的分布式网络有关.
- 对于社会处理而言,DLPFC的一个小而可变的区域可能解释了它在之前的群组分析中被低估的原因.
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