相关实验视频

Updated: Jun 23, 2026

Enrichment of Detergent-insoluble Protein Aggregates from Human Postmortem Brain
09:35

Enrichment of Detergent-insoluble Protein Aggregates from Human Postmortem Brain

Published on: October 24, 2017

12.8K

在,α-Synuclein和Aβ40中通过精子对聚合相关相互作用的残留特异调节

Debasis Saha, Sun Xun, Jinghui Luo

    bioRxiv : the preprint server for biology
    |January 9, 2026
    PubMed
    概括

    精子 (Spm) 通过结合到特定部位来影响涉及神经退行性疾病的内在失调蛋白 (IDP),根据序列和位置抑制或促进聚合. 这揭示了一个细微的机制,超出了简单的电荷相互作用.

    更多相关视频

    Fractionation for Resolution of Soluble and Insoluble Huntingtin Species07:08

    Fractionation for Resolution of Soluble and Insoluble Huntingtin Species

    Published on: February 27, 2018

    10.0K
    Exogenous Administration of Microsomes-associated Alpha-synuclein Aggregates to Primary Neurons As a Powerful Cell Model of Fibrils Formation09:16

    Exogenous Administration of Microsomes-associated Alpha-synuclein Aggregates to Primary Neurons As a Powerful Cell Model of Fibrils Formation

    Published on: June 26, 2018

    8.0K

    相关概念视频

    Amyloid Fibrils03:03

    Amyloid Fibrils

    Amyloid fibrils are aggregates of misfolded proteins.  Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils. 
    Amyloid deposits were observed as early as 1639 in the liver and the spleen.   In 1854, Rudolph Virchow performed iodine staining, normally used to...
    Amyloid Fibrils03:03

    Amyloid Fibrils

    Amyloid fibrils are aggregates of misfolded proteins.  Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils. 
    Amyloid deposits were observed as early as 1639 in the liver and the spleen.   In 1854, Rudolph Virchow performed iodine staining, normally used to...