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Updated: Jan 13, 2026

Identification of Transcription Factor Regulators using Medium-Throughput Screening of Arrayed Libraries and a Dual-Luciferase-Based Reporter
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Identification of Transcription Factor Regulators using Medium-Throughput Screening of Arrayed Libraries and a Dual-Luciferase-Based Reporter

Published on: March 27, 2020

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IKAROS基因调控网络揭示ERG是B细胞急性淋巴细胞白血病的脆弱性

Hana Paculova, Alyssa Richman, Joseph Boyd

    bioRxiv : the preprint server for biology
    |January 9, 2026
    PubMed
    概括

    在IKZF1 (IKAROS) 突变驱动B细胞急性淋巴细胞白血病 (B-ALL). 恢复IKAROS抑制ERG,白血病生长的关键因素,揭示ERG作为高风险B-ALL的治疗标.

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