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精准医学时代的骨髓瘤管理:书法测量分析和临床进展 (2015-2024)
The archives of bone and joint surgery
|January 9, 2026
概括
骨髓瘤研究正在增长,新的成像,生物标志物和个性化疗法,如向治疗和免疫疗法,显示出有前途. 未来的工作应该验证这些精确方法,以获得更好的患者结果.
科学领域:
- 在瘤学瘤学.
- 图书统计学 图书统计学
- 翻译医学是一种翻译医学.
背景情况:
- 骨髓瘤是一种高度恶性骨瘤,缺乏有效的治疗方法,需要新的治疗策略.
- 近年来,研究成果有所增加,强调需要对进展情况进行更新评估.
- 精准医学和个性化治疗正在成为骨髓瘤研究的关键领域.
研究的目的:
- 审查2015-2024年骨髓瘤研究中的文献统计趋势.
- 检查临床发展,重点关注精准医学和个性化治疗.
- 确定骨髓瘤治疗中的关键研究主题和新兴创新.
主要方法:
- 从科学网络核心集合 (2015-2024) 中对17,476篇出版物的图书法分析.
- 使用Bibliometrix R包评估出版趋势,国际合作和研究主题.
- 对诊断成像,生物标志物,化疗耐药性,向疗法,免疫疗法和手术技术的进展进行临床审查.
主要成果:
- 骨髓瘤的出版物稳步增加,在2021年达到顶峰,其中主要贡献来自中国,美国,日本,印度和意大利.
- 关键的研究主题包括亡,转移,化疗耐药性和免疫疗法.
- 动态MRI,PET/CT,遗传生物标志物 (TP53,RB1,MYC),向疗法 (激酶抑制剂,ADC) 和免疫疗法 (CAR T细胞,ICI) 的进展显著有前途.
结论:
- 图书统计数据和临床进展强调了个性化骨髓瘤管理的重要性.
- 预测成像生物标志物和精确向治疗对于改善患者的治疗结果至关重要.
- 未来的研究应该优先考虑对这些个性化方法的临床验证.
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