报告偏差在与内镜与显微镜解压相关的系统性审查和元分析中普遍存在:系统性审查和元分析
Pranit Kumaran1, David McCavitt1, Zachary Singh1
1Department of Orthopaedic Surgery, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.
Journal of spine surgery (Hong Kong)
|January 9, 2026
概括
在比较腰椎脊柱狭窄症 (LSS) 的内解压 (ED) 和显微解压 (MD) 的研究摘要中,脊柱是普遍存在的. 所有审查的系统审查都显示质量低且有偏见,影响了ED与MD比较的可靠性.
科学领域:
- 神经外科 神经外科
- 基于证据的医学基于证据的医学.
- 医学研究方法学 医学研究方法学
背景情况:
- 腰椎脊柱狭窄 (LSS) 的手术治疗包括较新的微创内解压 (ED) 和显微解压 (MD).
- 由于缺乏大型,高质量的随机对照试验,对评估ED和MD的研究存在潜在的偏见或旋转的担忧.
- 这项研究调查了系统性审查和元分析的摘要中旋转的流行情况,比较LSS的ED和MD.
研究的目的:
- 在系统综述和元分析摘要中分析旋转的患病率,比较腰椎缩 (LSS) 的内解压 (ED) 和显微解压 (MD).
- 通过AMSTAR 2分类来评估这些系统审查的质量.
主要方法:
- 在PubMed,科学网络和Scopus中使用PRISMA指南确定了系统性审查.
- 摘要分析了15种常见的旋转类型的发生率;全文使用AMSTAR 2进行了评估.
- 收集了研究的人口统计和指标,并使用了费舍尔的精确测试进行比较.
主要成果:
- 包含了10项系统性审查,所有这些审查都显示出至少一种类型的旋转.
- 最常见的旋转类型是"非统计学显著结果的结论声明等价性"和"有效性结果的选择性报告",每项都在50%的研究中发现.
- 根据AMSTAR 2标准,所有10项研究都获得了"非常低"的质量评级.
结论:
- 在比较腰椎脊柱狭窄症 (LSS) 的内解压 (ED) 和显微解压 (MD) 的摘要中,脊柱高度流行.
- 评估的系统审查表明方法质量较低,表明其调查结果可能不可靠.
- 需要进一步进行高质量的研究,以便为LSS治疗提供ED和MD的公正比较.
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