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Updated: Jan 13, 2026

Isolation, Characterization, and Purification of Macrophages from Tissues Affected by Obesity-related Inflammation
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Isolation, Characterization, and Purification of Macrophages from Tissues Affected by Obesity-related Inflammation

Published on: April 3, 2017

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肥胖诱导的型脂肪细胞死亡导致TREM2-依赖的巨细胞功能障碍和脂肪组织炎症

Cheoljun Choi1, Junhyuck Lee1, Gyeongran Park1

  • 1College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 08826, Republic of Korea.

iScience
|January 9, 2026
PubMed
概括

在肥胖症中,热性脂肪细胞死亡导致TREM2分泌,损害巨细胞功能并促进炎症. 抑制ADAM10/17可以通过减少TREM2裂变和增强细胞化来改善代谢健康.

关键词:
免疫反应的免疫反应.分子相互作用分子相互作用.分子网络是分子网络.

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