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Updated: Jan 13, 2026

Microfluidic On-chip Capture-cycloaddition Reaction to Reversibly Immobilize Small Molecules or Multi-component Structures for Biosensor Applications
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控制生物对等的聚合物纳米酶的细胞内和细胞外定位

Cristina-Maria Hirschbiegel1, Mathangi Shrikanth1, Yagiz Anil Cicek1

  • 1Department of Chemistry, University of Massachusetts Amherst 710N. Pleasant St. Amherst MA 01003 USA rotello@umass.edu.

Chemical science
|January 9, 2026
PubMed
概括

研究人员开发了带电的聚合物纳米颗粒 (聚酶) 来控制细胞内或外的生物对等脱反应. 这种向的药物激活通过结合细胞内和细胞外的药物释放,显著增强了癌细胞的杀死.

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Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...
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