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Updated: Jan 13, 2026

Methods for Evaluating the Role of c-Fos and Dusp1 in Oncogene Dependence
10:09

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高TERF2表达与预后不佳有关,其抑制减轻了急性髓性白血病的进展

Lihua Yao1,2, Xiaozhong Wang1,2

  • 1Jiangxi Province Key Laboratory of Immunology and Inflammation, Jiangxi Provincial Clinical Research Center for Laboratory Medicine, Department of Clinical Laboratory, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.

Translational cancer research
|January 9, 2026
PubMed
概括

端粒重复结合因子2 (TERF2) 在急性髓性白血病 (AML) 中过度表达,与预后不佳相关. 向TERF2抑制AML细胞生长并增强cuproptosis,提供了一个新的治疗策略.

关键词:
急性髓性白血病 (AML) 是一种疾病.这就是CDKN2A.通过E2F路径.这就是cuproptosis.端粒重复结合因子2 (TERF2) 的作用.

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