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Updated: May 12, 2026

Nanomechanics of Drug-target Interactions and Antibacterial Resistance Detection
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迪哈尔科基尼德菲达克索米辛衍生品,以检测在细菌中通过醇介导的吸收

Anastassia Kraimps1, Tizian Griesser2, Rui Wang2

  • 1Department of Chemistry, University of Zurich, Zurich 8057, Switzerland.

ACS infectious diseases
|January 9, 2026
PubMed
概括

科学家们通过 thiol-mediated uptake (TMU) 增强了fidaxomicin (Fdx) 的传递到细菌细胞中. 含有二硫化物的Fdx衍生物显示出更好的活性,这表明TMU是一种有前途的抗生素输送策略.

关键词:
这些是二硫化物.这就是fidaxomicin.自然产品是自然产品的产品.半合成是一种半合成.通过硫醇介导的吸收.

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