通过促进APOE表达和调节PI3K/AKT/FOXO1通路,SERPINA3促进质母细胞瘤的进展

LiLi Wang1, Lin Qu, Hui Sun

  • 1Department of Oncology, Shandong Provincial Key Medical and Health Discipline, Qingdao Central Hospital, University of Health and Rehabilitation Sciences, Qingdao City, Shandong Province, China.

Neurology India
|January 9, 2026
PubMed
概括

血清蛋白酶抑制剂A3 (SERPINA3) 通过增加阿波利波蛋白E (APOE) 和激活PI3K/AKT/FOXO1通路来促进质母细胞瘤 (GBM) 的生长. 这项研究阐明了SERPINA3的解释.

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