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Updated: Jan 13, 2026

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集成蛋白介导的TIMP1信号重新编程肝脏巨细胞,加速结肠直肠癌转移

Jialiang Liu1,2, Liming Zhao1, Lin Wang3

  • 1Department of Colorectal Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100020, China.

Cells
|January 9, 2026
PubMed
概括

结肠直肠癌 (CRC) 肝脏转移是由金属蛋白酶-1 (TIMP1) 的组织抑制剂促进的. TIMP1将巨细胞重新编程,以创建一个前转移性利基,提供一个潜在的治疗点.

关键词:
M2巨细胞的两极分化时间表1 TIMP1结肠直肠癌是什么意思肝脏转移的发生.在前转移前的利基.

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