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Updated: Jan 13, 2026

Accelerated Type 1 Diabetes Induction in Mice by Adoptive Transfer of Diabetogenic CD4+ T Cells
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(TCRαβ+) 双阴性T细胞在1型糖尿病中

Dimitri Poddighe1, Assel Mussayeva2, Kuanysh Dossybayeva2

  • 1College of Health Sciences, VinUniversity, Vinhomes Ocean Park, Gia Lam, Hanoi 100000, Vietnam.

Cells
|January 9, 2026
PubMed
概括

双阴性T (DNT) 细胞,特别是TCRαβ+,在1型糖尿病 (T1DM) 的小鼠模型中表现出保护作用. 这些细胞可能会抑制免疫介导的胰腺β细胞破坏,突出显示它们的潜在治疗意义.

关键词:
在CD4−CD8− T细胞中.DN T 细胞 DN T 细胞DNT 细胞是 DNT 细胞.在 NKT 细胞中.在NOD小鼠中.自免疫性糖尿病是什么?1型糖尿病是第一类糖尿病.双阴性T细胞是双阴性T细胞.

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