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Updated: Jan 13, 2026

Detection of Disease-associated α-synuclein by Enhanced ELISA in the Brain of Transgenic Mice Overexpressing Human A53T Mutated α-synuclein
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Detection of Disease-associated α-synuclein by Enhanced ELISA in the Brain of Transgenic Mice Overexpressing Human A53T Mutated α-synuclein

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当蛋白质发生MAD时 - 错误折叠,放大,检测:α-Synuclein病理生理学的进步和RT-QuIC检测

Naďa Labajová1, Adam Polák2, Ondrej Cehlár2

  • 1Institute of Neuroimmunology, Slovak Academy of Sciences, Bratislava, Slovakia. nada.labajova@savba.sk.

Molecular neurobiology
|January 9, 2026
PubMed
概括

阿尔法-同核素 (α-Syn) 错误折叠在同核素病变中驱动神经退行. 实时震动诱导转换 (RT-QuIC) 试验检测α-Syn种子,用于早期诊断.

关键词:
聚合是一种聚合.神经退行发生神经退行.帕金森病是帕金森氏症的一种疾病.美国人 美国人 RT-QuICIC合成核蛋白病变 (Synucleinopathies) 是一种同核蛋白病变.α-Synuclein 是一种蛋白质.

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