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Updated: Jan 13, 2026

A Familial Hypercholesterolemia Human Liver Chimeric Mouse Model Using Induced Pluripotent Stem Cell-derived Hepatocytes
10:56

A Familial Hypercholesterolemia Human Liver Chimeric Mouse Model Using Induced Pluripotent Stem Cell-derived Hepatocytes

Published on: September 15, 2018

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机会性基因组查家族高胆固醇血症以改善低密度脂蛋白胆固醇:一项随机临床试验

Jason L Vassy1,2, Charles A Brunette1,2, Thomas Yi1

  • 1Veterans Affairs (VA) Boston Healthcare System, Boston, Massachusetts.

JAMA network open
|January 9, 2026
PubMed
概括

针对家族性高胆固醇血症 (FH) 的机会性基因组查在这个RCT中没有显著降低LDL-C水平. 然而,即时的遗传结果显示出潜在的小到中等益处,需要进一步调查.

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