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在瘤发生过程中MTAP删除:一种合成死亡情景

Jordi Rodon1, Melissa L Johnson2, Ben George3

  • 1The University of Texas MD Anderson Cancer Center Houston, Texas United States.

Cancer research
|January 9, 2026
PubMed
概括

癌症中的甲基氨酸酸化酶 (MTAP) 缺失造成了脆弱性. 针对PRMT5通路的新疗法利用了这一点,通过合成致死性选择性杀死癌细胞.

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