关于在儿科血小板输血中新输血值的建议:血小板质量测量
Ceren Kılcı1, Fatma Burcu Belen Apak1, Meriç Ergene2
1Department of Pediatrics, Division of Pediatric Hematology and Oncology, Baskent University School of Medicine, Ankara, Turkey.
概括
从平均血小板体积和数量计算出血小板质量值,可以有效指导儿科输血. 这种方法在预防出血或成本方面没有差异,可能降低发病率和费用.
科学领域:
- 儿科血液学 儿科血液学
- 输血医学 输血医学
背景情况:
- 儿童血小板输血的决定取决于血小板缺血的病因和并发症.
- 血小板质量值 (MPV x 血小板计数) 显示出新生儿输血的前景.
研究的目的:
- 评估血小板质量值对儿科患者输血的有效性和适当性.
- 为了比较与血小板质量值与传统值相关的结果和成本.
主要方法:
- 从2017年1月到2019年1月,对82名儿科患者 (0-18岁) 的183例血小板输血进行了回顾性分析.
- 输血类型的评估 (预防性与治疗性),门坚持,以及预防出血的有效性.
- 基于对血小板质量值的遵守结果的比较.
主要成果:
- 94%的输血是预防性的,6%是治疗性的.
- 在达到血小板质量值的输血和没有达到血小板质量值的输血之间,在预防出血或成本效益方面没有发现显著差异 (p > 0.05).
- 17.7%的输血不达到定义的血小板质量值.
结论:
- 类似于新生儿使用的血小板质量值,可以有效地应用于儿科患者.
- 实施这些门值可能会降低与输血相关的发病率和医疗保健成本,而不会影响疗效.
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