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患有急性淋巴细胞白血病的儿童和青少年手握强度和身体构成:一个横截面研究
Emilaine Brinate Bastos1, Wanélia Vieira Afonso2, Gabriel Nathan da Costa Dias1
1Josué de Castro Nutrition Institute (INJC), Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, RJ, Brazil; Martag ão Gesteira InstituteofPediatricsandPuericulture (IPPMG), Federal Universityof Rio de Janeiro (UFRJ), Rio de Janeiro, RJ, Brazil.
Nutrition (Burbank, Los Angeles County, Calif.)
|January 9, 2026
概括
在患有急性淋巴细胞白血病的儿童中,较低的肌肉质量和较高的体重指数与手握强度的降低有关. 生活质量与手握强度没有相关性.
科学领域:
- 儿科瘤学 儿科瘤学
- 身体组成分析 身体成分分析
- 肌肉骨健康 肌肉骨健康
背景情况:
- 急性淋巴细胞白血病 (ALL) 可以影响孩子的整体健康,包括身体状况.
- 了解影响肌肉力量的因素对于管理ALL幸存者的长期健康至关重要.
研究的目的:
- 调查儿童ALL患者体质指数 (BMI),身体组成,生活质量 (QoL) 和握力 (HGS) 之间的关联.
- 在这个人群中确定肌肉表现的关键预测因素.
主要方法:
- 这是一项跨截面的多中心研究,涉及44名患有ALL的儿科患者 (5-18岁).
- 量子回归模型被用来分析BMI,身体组成 (手臂肌面积[AMA],手臂肌周长[AMP]),QoL和HGS之间的关系.
- 统计学意义被设定为P < 0.05.05.
主要成果:
- 在HGS和手臂周长 (r = 0.703),AMA (r = 0.814) 和AMP (r = 0.815) 之间发现了显著的正相关性.
- 在所有分析的量度中,AMA,AMP和年龄与HGS有积极关联.
- 身体质量指数 (BMI) 在所有量级中显示出与HGS的负相关性,尽管超过一半的队列超重或肥胖.
结论:
- 手臂肌肉面积和周长是儿童ALL患者手握强度的重要决定因素.
- 身体组成和年龄是影响肌肉表现的关键因素,而生活质量没有显著的相关性.
- 在这个患者群体中,较高的BMI与较低的手握强度有关,这强调了监测身体成分的重要性.
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