呼吸器肌肉训练对多发性硬化症的呼吸功能和疲劳的影响:系统性审查和元分析
Yunji Chen1, Kun Meng2, Guole Jiang1
1Basic Education College, National University of Defense Technology, Changsha, Hunan, China.
Multiple sclerosis and related disorders
|January 9, 2026
概括
呼吸道肌肉训练 (RMT) 在患有多发性硬化症 (MS) 的个体中显著改善呼吸系统的强度和功能. 虽然它减少了功能性疲劳,但它对整体疲劳严重性的影响是有限的,这支持其在MS康复中使用.
科学领域:
- 神经学 神经学
- 康复医学 康复医学 康复医学
- 肺部病理学 肺部病理学
背景情况:
- 多发性硬化症 (MS) 是一种慢性神经疾病,影响中枢神经系统.
- 呼吸道并发症,包括肌肉衰弱和疲劳,在MS患者中很常见.
- 这些呼吸道问题可以显著影响生活质量和功能能力.
研究的目的:
- 系统地评估呼吸器肌肉训练 (RMT) 在改善呼吸功能和减轻患有多发性硬化症的个体疲劳方面的有效性.
- 综合随机对照试验 (RCT) 和准RCT的证据,以确定RMT对关键呼吸和疲劳指标的影响.
主要方法:
- 按照PRISMA 2020的指导方针,在五个主要数据库 (PubMed/MEDLINE,科学网,Cochrane图书馆,SPORTDiscus,Scopus) 进行了系统的文献搜索.
- 包括的研究是RCT和准RCT,涉及患有MS的成年人接受隔离RMT (呼吸,呼吸或组合) 至少4周.
- 评估的主要结果包括呼吸功能 (MIP,MEP,FEV1,FVC) 和疲劳 (FSS,MFIS),数据使用元分析进行综合.
主要成果:
- 分析了与433名参与者的15项研究,表明RMT显著增强了呼吸肌肉强度 (MEP,MIP) 和肺功能 (FEV1,FVC).
- RMT导致修改疲劳影响量表 (MFIS) 的所有子量表显著减少疲劳,包括身体,认知和心理社会方面.
- 通过疲劳严重程度表 (FSS) 测量的疲劳严重程度没有显著改善.
结论:
- 呼吸道肌肉训练 (RMT) 是一种有效的干预措施,可以改善MS患者的呼吸道肌肉强度,肺功能,并减少功能性疲劳.
- 这些发现表明RMT可以成为MS患者综合康复计划的宝贵组成部分.
- 建议使用标准化协议进行进一步的研究,以确认长期益处,并优化MS管理的RMT策略.
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