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Updated: Jan 13, 2026

Protocol for the Solid-phase Synthesis of Oligomers of RNA Containing a 2'-O-thiophenylmethyl Modification and Characterization via Circular Dichroism
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作为终端灭菌技术的玛辐射对寡核酸的稳定性的影响

Tim Paumen1, Bart Croonenborghs2, Erik Haghedooren2

  • 1KU Leuven - University of Leuven, Department of Pharmaceutical and Pharmacological Sciences, Pharmaceutical Analysis, Herestraat 49, O&N2, PB 923, 3000 Leuven, Belgium.

International journal of pharmaceutics
|January 9, 2026
PubMed
概括

马辐射可以在水溶液中灭菌寡核酸. 令人惊的是,这种方法在没有添加任何辐射保护因素的情况下是最有效的,这与预期相反.

关键词:
生物制药产品 生物制药产品降解降解是一种降解.类型:homo-oligonucleotides 类型:homo-oligonucleotides 类型:homo-oligonucleotides 类型:homo-oligonucleotides 类型:homo-oligonucleotides 类型:homo-oligonucleotides 类型:homo-oligonucleotides 类型:homo-oligonucleotides 类型:homo-oligonucleotides 类型:homo-oligonucleotides 类型:homo-oligonucleotides在IP-RPLC中使用IP-RPLC.终端杀菌的绝育方法

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