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Updated: Jan 13, 2026

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在父母暴露于后,小鼠的生殖腺中发生了代际性别特异的转录组变化

Nelly Banda1, Kanami Watanabe1, John Yabe2

  • 1Laboratory of Toxicology, Department of Environmental Veterinary Sciences, Faculty of Veterinary Medicine, Hokkaido University, Kita 18, Nishi 9, Kita-ku, Sapporo 060-0818, Japan.

Reproductive toxicology (Elmsford, N.Y.)
|January 9, 2026
PubMed
概括

父母的 (Pb) 暴露会改变生殖腺中的后代基因表达. 这些转录组变化表明潜在的遗传效应,影响生殖系生物学和发育.

关键词:
不孕症 不孕不育 不孕不育 不孕不育母亲的 母亲的 母亲父亲的父性 父亲的父性Pb Pb Pb Pb Pb Pb Pb Pb Pb Pb Pb Pb Pb Pb Pb Pb Pb Pb Pb Pb Pb Pb Pb Pb Pb在RNASeq中使用.

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Although the genetic makeup of an organism plays a major role in determining the phenotype, there are also several environmental factors, such as temperature, oxygen availability, presence of mutagens, that can alter an organism’s phenotype.
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
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