运动增强疗程是否有效地保留了多发性硬化症患者的运动诱导效应? 一个随机对照试验:MSBOOST试验的结果
Laurits Taul-Madsen1, L G Hvid2, F Sellebjerg3
1Exercise Biology, Department of Public Health, Aarhus University, Denmark.
Journal of science and medicine in sport
|January 9, 2026
概括
在患有多发性硬化症的人群中,炼增强剂没有保持身体功能或肌肉力量. 然而,增强剂会确实保持了初始训练的有氧能力改善.
科学领域:
- 神经学 神经学
- 康复医学 康复医学 康复医学
- 运动科学 运动科学
背景情况:
- 运动训练可以提高患有多发性硬化症 (PWMS) 的人的身体功能.
- 运动对有氧能力和肌肉力量的益处在停止后会减少.
- 保持身体功能对于PWMS的整体健康状况至关重要.
研究的目的:
- 为了确定运动增强疗程 (EBS) 是否可以保持运动诱导的PWMS改善.
- 评估EBS对身体功能,有氧能力和肌肉力量的长期影响.
主要方法:
- 一个多中心随机对照试验 (RCT) 涉及94名PWMS.
- 参与者进行了12周的有氧训练 (AT) 或抵抗训练 (RT).
- 训练后,参与者被随机分配到40周接受EBS或通常的护理,以身体功能 (6MWT和5STS复合得分),有氧能力和肌肉力量作为结果.
主要成果:
- 在复合的身体功能得分中,没有发现群体之间的显著差异.
- 有氧能力没有显示组间差异,但ATboost组保持了改善.
- 肌肉强度在各组之间没有差异,对于RTboost或RTuc.没有观察到组内变化.
结论:
- 在PWMS中,炼增强器 (EBS) 没有显著影响维持身体功能或肌肉力量.
- 无论干预组如何,肌肉力量都保持不变.
- 在ATboost组中,EBS成功地保持了运动诱导的有氧能力增加.
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