在活体捐赠者脏移植中,与延迟的移植功能相关的术内平均动脉压
Chinnarat Pongpruksa1, Nutchanok Khampitak2, Suphamai Bunnapradist3
1Department of Anesthesiology and Perioperative Medicine, Ronald Reagan UCLA Medical Center, David Geffen School of Medicine at UCLA, Los Angeles, California; Department of Anesthesiology, Rajavithi Hospital, Bangkok, Thailand; College of Medicine, Rangsit University, Bangkok, Thailand.
Transplantation proceedings
|January 9, 2026
概括
在移植期间保持最佳 perfusion 是至关重要的. 这项研究发现,低于85毫米平的手术内平均动脉血压 (MAP) 与移植接受者的延迟移植功能 (DGF) 有关.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 移植手术 移植手术
- 关键护理医学 关键护理医学
背景情况:
- 在移植手术期间,最佳移植输液是必不可少的.
- 平均动脉血压 (MAP) 是一个关键的手术内监测参数.
- 延迟移植功能 (DGF) 是一种影响长期移植结果的并发症.
研究的目的:
- 调查各种平均动脉血压 (MAP) 值与延迟移植功能 (DGF) 风险之间的关联.
- 分析在特定的MAP值度过的累积分钟对成年活体捐赠者脏移植患者DGF的影响.
主要方法:
- 在2013年至2024年期间,在加州大学洛杉矶分校接受活体捐赠者脏移植的1314名成年患者的回顾性分析.
- 在重灌前和后阶段,在多个值和累积持续时间的平均动脉血压 (MAP) 的评估.
- 延迟移植功能 (DGF) 被定义为需要在移植 (KT) 后7天内进行透析.
主要成果:
- 在1314名患者中,总体DGF率为5.0%.
- 42%的患者经历了至少1分钟的MAP≤60毫米血.
- 在MAP值≤60至85mmHg之间花费的分钟增加与DGF有关;与DGF相关的回后MAP≤60和≤85mmHg的调整持续时间分别为3分钟和25分钟.
结论:
- 术内平均动脉血压 (MAP) 低于85mmHg与移植后延迟移植功能 (DGF) 的风险增加有关.
- 后MAP的特定最小持续时间,特别是≤60 mm Hg (3分钟) 和≤85 mm Hg (25分钟),与DGF有关.
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