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Updated: Jan 13, 2026

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在上皮质修复中,托芬代谢守门:GPR35-KLF5电路解码粘膜损伤信号,用于修复编程

Biao Xie1,2, Meimei Wang3, Yaping Xiao3

  • 1Department of Gastroenterology, Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, PR China.

Cell death & disease
|January 9, 2026
PubMed
概括

研究人员发现了一种新的机制,G蛋白结合受体35 (GPR35) 通过感知托代谢来检测肠道损伤. 这种传感通过KLF5在肠上皮细胞 (IEC) 中启动修复程序,提供潜在的性结肠炎治疗方法.

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