对基于LLM的通用系统在预测试管婴儿结果方面的比较性能的研究
Can Dinç1, Ömer Faruk Öz2, Saltuk Buğra Arıkan2
1Department of Gynecology and Obstetrics, Akdeniz University, Antalya, Turkey. candinc@akdeniz.edu.tr.
Journal of assisted reproduction and genetics
|January 9, 2026
概括
像ChatGPT,DeepSeek和Gemini这样的通用AI模型在预测体外受精 (IVF) 结果方面显示出有限的准确性. 它们目前的性能不足以支持IVF的临床决策,需要进一步的验证和研究.
科学领域:
- 生殖医学 生殖医学
- 人工智能的人工智能
- 临床决策支持 临床决策支持
背景情况:
- 一般用途的大型语言模型 (LLM) 显示出临床决策支持的前景.
- 在预测体外受精 (IVF) 结果方面,LLM的表现没有得到很好的描述.
- 这项研究评估了三个可访问的LLM:ChatGPT,DeepSeek和Gemini.
研究的目的:
- 为了比较ChatGPT,DeepSeek和Gemini的即时性能.
- 评估LLM在预测关键IVF临床和实验室结果方面的能力.
- 评估AI在生殖医学中的临床决策支持方面的潜力.
主要方法:
- 对1473个自身体外受精/ICSI周期的回顾性分析.
- 通过网络接口提交给LLM的标准化患者简历.
- 用准确度,平均绝对误差和ROC AUC评估各种IVF结果的性能.
主要成果:
- 双子座在预测刺激方案和胚胎数量方面表现出最高的准确性.
- 对于卵细胞计数预测,DeepSeek 的数值误差最低.
- 临床怀孕预测具有挑战性;双子座实现了最高的AUC (0.711).
结论:
- 一般用途的人工智能系统在预测试管婴儿结果方面显示出可变和低于最佳的性能.
- 目前的LLM缺乏在IVF安全临床实施的可靠性.
- 在临床使用之前,需要在受控研究环境中进一步验证.
相关概念视频
In Vitro Fertilization
874
In vitro fertilization (IVF) is a form of assisted reproductive technology where an egg is fertilized with sperm in a controlled laboratory environment before transferring the resulting embryo into the uterus. This process is designed to help individuals and couples experiencing difficulties conceiving.
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
874
Infertility in Females
3.6K
Female infertility is defined as the inability to conceive after a year of regular, unprotected intercourse and affects about 10–15% of couples worldwide. The primary cause of female infertility is ovulatory disorders, which hinder the release of eggs. These disorders can be classified as hypothalamic amenorrhea, polycystic ovarian syndrome (PCOS), premature ovarian failure, and hyperprolactinemic anovulation disorders.
Endometriosis, a condition characterized by abnormal growth of...
Endometriosis, a condition characterized by abnormal growth of...
3.6K


