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正鼻腔生物活性挥发物及其对唾液的影响:试点研究
Wiktoria Potocka1,2, Zainab Assy3,4, Marja L Laine4
1Department of Oral Biochemistry, Academic Centre for Dentistry Amsterdam, University of Amsterdam and VU University Amsterdam, Gustav Mahlerlaan, 3004, 1081 LA, Amsterdam, the Netherlands. w.potocka@acta.nl.
Clinical oral investigations
|January 9, 2026
概括
含有玄米和瓜亚科尔挥发物质的鼻吸入器在健康个体中增加了唾液流. 玄米还改善了口腔水分,这表明口腔干燥治疗的潜力.
科学领域:
- 嗅觉刺激是一种嗅觉刺激.
- 唾液腺生理学 唾液腺生理学
- 口腔健康 口腔健康
背景情况:
- 以前的研究表明,树脂中的挥发性物质可以刺激唾液流.
- 存在对新型挥发性 sialagogues 和标准化交付方法的需求.
研究的目的:
- 为了评估α-pinene,玄米,eugenol和瓜亚科尔挥发性物质的 sialagogic 作用.
- 评估这些化合物使用鼻吸入器进行嗅觉刺激.
主要方法:
- 健康的参与者 (n=12) 通过鼻吸入器吸入α-pinene,玄米,eugenol和guaiacol.
- 在吸入前和后测量了唾液流量,spinnbarkeit和口腔感觉.
- 使用安慰剂吸入器来评估潜在的安慰剂效应.
主要成果:
- 香和瓜亚科尔的吸入显著增加了唾液流 (p ≤ 0.01).
- 香的吸入改善了主观的口腔水分感觉 (p < 0.05).
- 安慰剂吸入器对唾液流量没有显著影响.
结论:
- 鼻腔吸入玄米挥发物有效增强唾液分泌和口腔水分.
- 巴西里看起来很有前途,作为口腔干燥的局部治疗方法.
- 对口腔干燥患者进行进一步的临床试验是有必要的.
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