在前结肠炎中,亚托皮性共发病率是否增加?
Nagihan Iskender1, Ismail Ozanli1, Nefise Nezihe Uluc1
1From the Division of Pediatric Allergy and Immunology, Kocaeli University Faculty of Medicine, Kocaeli, Türkiye.
Allergy and asthma proceedings
|January 9, 2026
概括
食物蛋白诱导的过敏性口腔炎 (FPIAP) 与更高的喘发病率,过敏性鼻炎和IgE介导的食物过敏有关. 这凸显了承认FPIAP的重要性.
科学领域:
- 儿科过敏和免疫学
- 胃肠病学 胃肠病学
- 免疫学 免疫学 免疫学
背景情况:
- "过敏征程"描述了过敏疾病的进展,但研究往往忽略了非IgE介导的食物过敏 (非IgE-FA).
- 非IgE-FA的影响,如食物蛋白诱导过敏直肠炎 (FPIAP),对过敏过程的影响还不清楚.
研究的目的:
- 调查FPIAP与其他过敏疾病的发展之间的关联.
- 确定患有FPIAP的儿童过敏征程的潜在预测因素.
主要方法:
- 一项回顾性研究比较了84名被诊断患有FPIAP的患者 (跟踪时间≥3年) 与89名年龄和性别匹配的对照.
- 收集的数据包括喘,过敏性鼻炎 (AR),IgE介导的食物过敏 (IgE-FA) 和亚托皮炎等同时发生的过敏性疾病的患病率.
主要成果:
- 与对照组相比,FPIAP患者的喘率 (29.8%与14.6%相比),AR (29.8%与13.5%) 和IgE-FA (15.5%与3.4%) 显著增加.
- 2年以下的FPIAP患者 (38.6%与10.6%) 的亚托皮炎患病率更高.
- 发作时吐预测了喘;在FPIAP组中,孕产妇鼻炎和延迟补充养预测了AR.
结论:
- FPIAP与患喘,AR和IgE-FA的风险增加有关,这表明它在过敏过程中发挥了作用.
- 这些发现强调需要提高临床意识,以了解FPIAP与其他过敏疾病的潜在共发生.
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