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Updated: Jan 13, 2026

2D and 3D Human Induced Pluripotent Stem Cell-Based Models to Dissect Primary Cilium Involvement during Neocortical Development
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人类多能干细胞模型的弗里德里希的缺氧:创新,考虑,和未来的前景

Ha Thi Nguyen1, Marek Napierala1, Jill S Napierala2

  • 1Department of Neurology, O'Donnell Brain Institute, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX, 75390, USA.

Stem cell research & therapy
|January 9, 2026
PubMed
概括

弗里德里希缺氧症 (FRDA) 是一种影响神经系统和心脏的遗传性疾病,由低弗拉素 (FXN) 表达引起. 来自患者的干细胞为研究FRDA机制和开发疗法提供了新的模型.

关键词:
在体外分化中的差异化.星球细胞是星球细胞.心脏肌细胞是心脏肌细胞.疾病建模 疾病建模弗里德里希的过敏症是什么这些神经元是神经元.器官类动物 器官类动物多能干细胞是多能干细胞.贝塔细胞是β细胞.

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