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Updated: Jan 13, 2026

Assessment of Resistance to Tyrosine Kinase Inhibitors by an Interrogation of Signal Transduction Pathways by Antibody Arrays
07:42

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Published on: September 19, 2018

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在Uveal黑色素瘤中解开对Gαq通路抑制的抵抗机制:来自信号激活库查的见解

Simone Lubrano1,2, Rodolfo Daniel Cervantes-Villagrana1,2, Nadia Arang1,3

  • 1Moores Cancer Center, University of California San Diego, La Jolla, CA 92093, USA.

Cancers
|January 10, 2026
PubMed
概括

卵膜黑色素瘤细胞通过激活像JAK/STAT和PI3K/AKT/mTOR这样的补偿通路来适应向治疗. 将这些适应性网络与主要瘤信号一起定位,为晚期阴膜黑色素瘤治疗提供了一个有希望的策略.

关键词:
在 AKT AKT 里面.在BCL-XL之间.这是真实的,真实的,真实的.这就是MEK MEK.对于YAP/TEAD来说,这是一个很好的选择.河马的路径 河马的路径在mTOROR中使用mTOR.电阻的电阻是指电阻的电阻阴膜性黑色素瘤是什么

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